This was true following both the first and second doses. All volunteers had similar antibody responses to the vaccine. Results of these tests showed no correlation between the severity of symptoms and levels of antibodies produced by the vaccine. The volunteers reported that these symptoms increased in frequency after the second shot.Īfter each vaccination, antibody levels were also measured using a reliable assay. Symptoms included soreness at the vaccination site, weakness, headache, and body aches. The volunteers rated 12 symptoms on an intensity scale of 0 to 4. At the first monthly visit following each dose of the Pfizer/BioNTech vaccine, each volunteer completed a questionnaire about their physical reactions to the shot. Results were published recently in the journal Open Forum Infectious Diseases.Ī total of 206 healthy volunteers who work at Walter Reed National Military Medical Center in Bethesda, Md., enrolled in the study that began in August 2020.
So, a research collaboration including Frederick National Laboratory (FNL) and led by the Uniformed Services University of the Health Sciences (USU) conducted a single-center observational study to find out more. The relationship between a reaction to COVID-19 vaccines and the strength of antibody response to the vaccine has been somewhat uncertain. On the other hand, a lack of side-effects does not point to vaccine failure, according to a new study. You might have heard these things happen because your COVID-19 shot is working as it should. You may have had a sore arm, felt tired, or had a headache.
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